Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
5.8
USERS' SCORE
Good
Based on 4 Reviews
8.4
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D (as D3 Cholecalciferol)
50 mcg (2,000 IU)
250%
Top Medical Research Studies
0
We conducted a study to see if high-dose vitamin D3 could improve vascular health and reduce fatigue in individuals suffering from chronic fatigue syndrome (CFS). This was a well-structured trial involving 50 participants, all of whom met specific diagnostic criteria for CFS. Participants were divided into two groups: one received 100,000 units of vitamin D3 every two months, while the other received a placebo over a period of six months.
Despite a noticeable increase of 22 nmol/L in vitamin D levels for those who received the treatment compared to the placebo group, we found no significant benefits. There was no change in arterial stiffness, a key vascular health indicator, nor improvements in overall fatigue as measured by the Piper Fatigue scale.
In essence, our findings indicate that high-dose oral vitamin D3 does not offer the hoped-for relief in vascular function or fatigue for patients with chronic fatigue syndrome. This suggests that other therapeutic options may need to be explored for individuals suffering from this condition.
Despite a noticeable increase of 22 nmol/L in vitamin D levels for those who received the treatment compared to the placebo group, we found no significant benefits. There was no change in arterial stiffness, a key vascular health indicator, nor improvements in overall fatigue as measured by the Piper Fatigue scale.
In essence, our findings indicate that high-dose oral vitamin D3 does not offer the hoped-for relief in vascular function or fatigue for patients with chronic fatigue syndrome. This suggests that other therapeutic options may need to be explored for individuals suffering from this condition.
Read More
9.5
Vitamin D treatment enhances alertness
We explored the impact of vitamin D treatment on a case of excessive daytime sleepiness (EDS), specifically in the context of chronic fatigue syndrome. A 28-year-old woman was found to have low levels of vitamin D after experiencing four months of overwhelming fatigue and sleepiness, despite being tested for sleep disorders.
After starting vitamin D supplementation, her condition improved remarkably within just two weeks. Along with a boost in alertness, her associated symptoms like muscle pain and headaches began to fade. By the end of the treatment, her score on the Epworth Sleepiness Scale, which measures daytime sleepiness, dropped significantly, indicating much better daytime function.
This case suggests that vitamin D may play a role in improving symptoms commonly linked to chronic fatigue syndrome. While more research is needed to fully understand the mechanisms behind this improvement, our findings open the door to potentially screening patients with chronic fatigue for vitamin D deficiency to expedite treatment.
After starting vitamin D supplementation, her condition improved remarkably within just two weeks. Along with a boost in alertness, her associated symptoms like muscle pain and headaches began to fade. By the end of the treatment, her score on the Epworth Sleepiness Scale, which measures daytime sleepiness, dropped significantly, indicating much better daytime function.
This case suggests that vitamin D may play a role in improving symptoms commonly linked to chronic fatigue syndrome. While more research is needed to fully understand the mechanisms behind this improvement, our findings open the door to potentially screening patients with chronic fatigue for vitamin D deficiency to expedite treatment.
Read More
8
We conducted a double-blind, placebo-controlled trial to evaluate the effects of an oral food supplement (OFS) on long COVID patients, particularly focusing on chronic inflammation and fatigue. The supplement included components like rosehip, propolis, royal jelly, and zinc, with vitamin C being a key ingredient.
Through our two-month study, which involved giving participants either the OFS or a placebo, we made some interesting observations. Notably, patients who took the OFS experienced a significant reduction in inflammatory markers, which are often linked to chronic fatigue syndrome. This included improvements in the neutrophil-to-lymphocyte and monocyte-to-lymphocyte ratios.
We also noted a substantial increase in vitamin D levels among those taking the supplement, which correlated with enhanced quality of life and decreased fatigue as measured by the fatigue severity scale. Our findings suggest that the combination of ingredients in the OFS, particularly its vitamin D content, can help alleviate some symptoms associated with long COVID, especially chronic fatigue.
However, since the supplement included multiple active ingredients, isolating the specific impact of vitamin D on chronic fatigue syndrome is challenging. Still, the overall results indicate positive changes for patients dealing with the lingering effects of COVID.
Through our two-month study, which involved giving participants either the OFS or a placebo, we made some interesting observations. Notably, patients who took the OFS experienced a significant reduction in inflammatory markers, which are often linked to chronic fatigue syndrome. This included improvements in the neutrophil-to-lymphocyte and monocyte-to-lymphocyte ratios.
We also noted a substantial increase in vitamin D levels among those taking the supplement, which correlated with enhanced quality of life and decreased fatigue as measured by the fatigue severity scale. Our findings suggest that the combination of ingredients in the OFS, particularly its vitamin D content, can help alleviate some symptoms associated with long COVID, especially chronic fatigue.
However, since the supplement included multiple active ingredients, isolating the specific impact of vitamin D on chronic fatigue syndrome is challenging. Still, the overall results indicate positive changes for patients dealing with the lingering effects of COVID.
Read More
Most Useful Reviews
9
No more fatigue
Quality product. I have been purchasing from this shop for some time, and it is always delivered on time and well-packaged. The dosage was recommended by my doctor, and absorption is quick. This product is excellent for managing vitamin deficiency, especially since I don’t receive much sunlight. With 150 capsules in the bottle, I appreciate that it has no taste. Since starting it, I no longer feel chronic fatigue syndrome; it has made a significant difference in my energy levels.
Read More
9
Boosted energy levels
⭐⭐⭐⭐⭐ This vitamin D3 from Nature's Bounty is an excellent choice for immune support and bone health. It boasts high quality, optimal 2000 IU dosage per capsule, and convenient small capsules that are easy to swallow. After just a couple of weeks, I've experienced increased energy, significantly reduced fatigue symptoms, and noticed I'm getting sick much less often during winter. This product is a fantastic option for overall health, and I will certainly order it again!
Read More
7.5
Increased energy
Good composition, fast delivery, and high-quality packaging. The dosage is excellent, and the natural herbal ingredients are beneficial. The capsules are slightly large, but I find them easy to swallow as they have a citrus taste. I take one capsule daily with meals, alongside vitamin D3+K2, magnesium, and vitamin B6. I've begun to notice significant benefits; prior to taking it, I experienced headaches, nausea, and chronic fatigue syndrome throughout the day. After just 10 days, I've gained more energy, my headaches have ceased, and my mood has improved. I highly recommend it, especially for those interested in sports and diets, as omega-3 energises and replenishes what the body lacks.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
5.8
- All Researches
9.5
Vitamin D treatment enhances alertness
We explored the impact of vitamin D treatment on a case of excessive daytime sleepiness (EDS), specifically in the context of chronic fatigue syndrome. A 28-year-old woman was found to have low levels of vitamin D after experiencing four months of overwhelming fatigue and sleepiness, despite being tested for sleep disorders.
After starting vitamin D supplementation, her condition improved remarkably within just two weeks. Along with a boost in alertness, her associated symptoms like muscle pain and headaches began to fade. By the end of the treatment, her score on the Epworth Sleepiness Scale, which measures daytime sleepiness, dropped significantly, indicating much better daytime function.
This case suggests that vitamin D may play a role in improving symptoms commonly linked to chronic fatigue syndrome. While more research is needed to fully understand the mechanisms behind this improvement, our findings open the door to potentially screening patients with chronic fatigue for vitamin D deficiency to expedite treatment.
After starting vitamin D supplementation, her condition improved remarkably within just two weeks. Along with a boost in alertness, her associated symptoms like muscle pain and headaches began to fade. By the end of the treatment, her score on the Epworth Sleepiness Scale, which measures daytime sleepiness, dropped significantly, indicating much better daytime function.
This case suggests that vitamin D may play a role in improving symptoms commonly linked to chronic fatigue syndrome. While more research is needed to fully understand the mechanisms behind this improvement, our findings open the door to potentially screening patients with chronic fatigue for vitamin D deficiency to expedite treatment.
Read More
8
We conducted a double-blind, placebo-controlled trial to evaluate the effects of an oral food supplement (OFS) on long COVID patients, particularly focusing on chronic inflammation and fatigue. The supplement included components like rosehip, propolis, royal jelly, and zinc, with vitamin C being a key ingredient.
Through our two-month study, which involved giving participants either the OFS or a placebo, we made some interesting observations. Notably, patients who took the OFS experienced a significant reduction in inflammatory markers, which are often linked to chronic fatigue syndrome. This included improvements in the neutrophil-to-lymphocyte and monocyte-to-lymphocyte ratios.
We also noted a substantial increase in vitamin D levels among those taking the supplement, which correlated with enhanced quality of life and decreased fatigue as measured by the fatigue severity scale. Our findings suggest that the combination of ingredients in the OFS, particularly its vitamin D content, can help alleviate some symptoms associated with long COVID, especially chronic fatigue.
However, since the supplement included multiple active ingredients, isolating the specific impact of vitamin D on chronic fatigue syndrome is challenging. Still, the overall results indicate positive changes for patients dealing with the lingering effects of COVID.
Through our two-month study, which involved giving participants either the OFS or a placebo, we made some interesting observations. Notably, patients who took the OFS experienced a significant reduction in inflammatory markers, which are often linked to chronic fatigue syndrome. This included improvements in the neutrophil-to-lymphocyte and monocyte-to-lymphocyte ratios.
We also noted a substantial increase in vitamin D levels among those taking the supplement, which correlated with enhanced quality of life and decreased fatigue as measured by the fatigue severity scale. Our findings suggest that the combination of ingredients in the OFS, particularly its vitamin D content, can help alleviate some symptoms associated with long COVID, especially chronic fatigue.
However, since the supplement included multiple active ingredients, isolating the specific impact of vitamin D on chronic fatigue syndrome is challenging. Still, the overall results indicate positive changes for patients dealing with the lingering effects of COVID.
Read More
0
We conducted a study to see if high-dose vitamin D3 could improve vascular health and reduce fatigue in individuals suffering from chronic fatigue syndrome (CFS). This was a well-structured trial involving 50 participants, all of whom met specific diagnostic criteria for CFS. Participants were divided into two groups: one received 100,000 units of vitamin D3 every two months, while the other received a placebo over a period of six months.
Despite a noticeable increase of 22 nmol/L in vitamin D levels for those who received the treatment compared to the placebo group, we found no significant benefits. There was no change in arterial stiffness, a key vascular health indicator, nor improvements in overall fatigue as measured by the Piper Fatigue scale.
In essence, our findings indicate that high-dose oral vitamin D3 does not offer the hoped-for relief in vascular function or fatigue for patients with chronic fatigue syndrome. This suggests that other therapeutic options may need to be explored for individuals suffering from this condition.
Despite a noticeable increase of 22 nmol/L in vitamin D levels for those who received the treatment compared to the placebo group, we found no significant benefits. There was no change in arterial stiffness, a key vascular health indicator, nor improvements in overall fatigue as measured by the Piper Fatigue scale.
In essence, our findings indicate that high-dose oral vitamin D3 does not offer the hoped-for relief in vascular function or fatigue for patients with chronic fatigue syndrome. This suggests that other therapeutic options may need to be explored for individuals suffering from this condition.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
No more fatigue
Quality product. I have been purchasing from this shop for some time, and it is always delivered on time and well-packaged. The dosage was recommended by my doctor, and absorption is quick. This product is excellent for managing vitamin deficiency, especially since I don’t receive much sunlight. With 150 capsules in the bottle, I appreciate that it has no taste. Since starting it, I no longer feel chronic fatigue syndrome; it has made a significant difference in my energy levels.
Read More
9
Boosted energy levels
⭐⭐⭐⭐⭐ This vitamin D3 from Nature's Bounty is an excellent choice for immune support and bone health. It boasts high quality, optimal 2000 IU dosage per capsule, and convenient small capsules that are easy to swallow. After just a couple of weeks, I've experienced increased energy, significantly reduced fatigue symptoms, and noticed I'm getting sick much less often during winter. This product is a fantastic option for overall health, and I will certainly order it again!
Read More
7.5
Increased energy
Good composition, fast delivery, and high-quality packaging. The dosage is excellent, and the natural herbal ingredients are beneficial. The capsules are slightly large, but I find them easy to swallow as they have a citrus taste. I take one capsule daily with meals, alongside vitamin D3+K2, magnesium, and vitamin B6. I've begun to notice significant benefits; prior to taking it, I experienced headaches, nausea, and chronic fatigue syndrome throughout the day. After just 10 days, I've gained more energy, my headaches have ceased, and my mood has improved. I highly recommend it, especially for those interested in sports and diets, as omega-3 energises and replenishes what the body lacks.
Read More
7.5
Improved insomnia
I regularly buy this product for my mother. She reports that it's had a notable impact on her insomnia and symptoms of chronic fatigue syndrome. We're committed to purchasing it in the future, and I believe it offers good value for money.
Read More
Frequently Asked Questions
7.5
Increased energy
Good composition, fast delivery, and high-quality packaging. The dosage is excellent, and the natural herbal ingredients are beneficial. The capsules are slightly large, but I find them easy to swallow as they have a citrus taste. I take one capsule daily with meals, alongside vitamin D3+K2, magnesium, and vitamin B6. I've begun to notice significant benefits; prior to taking it, I experienced headaches, nausea, and chronic fatigue syndrome throughout the day. After just 10 days, I've gained more energy, my headaches have ceased, and my mood has improved. I highly recommend it, especially for those interested in sports and diets, as omega-3 energises and replenishes what the body lacks.
7.5
Improved insomnia
I regularly buy this product for my mother. She reports that it's had a notable impact on her insomnia and symptoms of chronic fatigue syndrome. We're committed to purchasing it in the future, and I believe it offers good value for money.
9
No more fatigue
Quality product. I have been purchasing from this shop for some time, and it is always delivered on time and well-packaged. The dosage was recommended by my doctor, and absorption is quick. This product is excellent for managing vitamin deficiency, especially since I don’t receive much sunlight. With 150 capsules in the bottle, I appreciate that it has no taste. Since starting it, I no longer feel chronic fatigue syndrome; it has made a significant difference in my energy levels.
9
Boosted energy levels
⭐⭐⭐⭐⭐ This vitamin D3 from Nature's Bounty is an excellent choice for immune support and bone health. It boasts high quality, optimal 2000 IU dosage per capsule, and convenient small capsules that are easy to swallow. After just a couple of weeks, I've experienced increased energy, significantly reduced fatigue symptoms, and noticed I'm getting sick much less often during winter. This product is a fantastic option for overall health, and I will certainly order it again!
8
We conducted a double-blind, placebo-controlled trial to evaluate the effects of an oral food supplement (OFS) on long COVID patients, particularly focusing on chronic inflammation and fatigue. The supplement included components like rosehip, propolis, royal jelly, and zinc, with vitamin C being a key ingredient.
Through our two-month study, which involved giving participants either the OFS or a placebo, we made some interesting observations. Notably, patients who took the OFS experienced a significant reduction in inflammatory markers, which are often linked to chronic fatigue syndrome. This included improvements in the neutrophil-to-lymphocyte and monocyte-to-lymphocyte ratios.
We also noted a substantial increase in vitamin D levels among those taking the supplement, which correlated with enhanced quality of life and decreased fatigue as measured by the fatigue severity scale. Our findings suggest that the combination of ingredients in the OFS, particularly its vitamin D content, can help alleviate some symptoms associated with long COVID, especially chronic fatigue.
However, since the supplement included multiple active ingredients, isolating the specific impact of vitamin D on chronic fatigue syndrome is challenging. Still, the overall results indicate positive changes for patients dealing with the lingering effects of COVID.
Through our two-month study, which involved giving participants either the OFS or a placebo, we made some interesting observations. Notably, patients who took the OFS experienced a significant reduction in inflammatory markers, which are often linked to chronic fatigue syndrome. This included improvements in the neutrophil-to-lymphocyte and monocyte-to-lymphocyte ratios.
We also noted a substantial increase in vitamin D levels among those taking the supplement, which correlated with enhanced quality of life and decreased fatigue as measured by the fatigue severity scale. Our findings suggest that the combination of ingredients in the OFS, particularly its vitamin D content, can help alleviate some symptoms associated with long COVID, especially chronic fatigue.
However, since the supplement included multiple active ingredients, isolating the specific impact of vitamin D on chronic fatigue syndrome is challenging. Still, the overall results indicate positive changes for patients dealing with the lingering effects of COVID.
0
We conducted a study to see if high-dose vitamin D3 could improve vascular health and reduce fatigue in individuals suffering from chronic fatigue syndrome (CFS). This was a well-structured trial involving 50 participants, all of whom met specific diagnostic criteria for CFS. Participants were divided into two groups: one received 100,000 units of vitamin D3 every two months, while the other received a placebo over a period of six months.
Despite a noticeable increase of 22 nmol/L in vitamin D levels for those who received the treatment compared to the placebo group, we found no significant benefits. There was no change in arterial stiffness, a key vascular health indicator, nor improvements in overall fatigue as measured by the Piper Fatigue scale.
In essence, our findings indicate that high-dose oral vitamin D3 does not offer the hoped-for relief in vascular function or fatigue for patients with chronic fatigue syndrome. This suggests that other therapeutic options may need to be explored for individuals suffering from this condition.
Despite a noticeable increase of 22 nmol/L in vitamin D levels for those who received the treatment compared to the placebo group, we found no significant benefits. There was no change in arterial stiffness, a key vascular health indicator, nor improvements in overall fatigue as measured by the Piper Fatigue scale.
In essence, our findings indicate that high-dose oral vitamin D3 does not offer the hoped-for relief in vascular function or fatigue for patients with chronic fatigue syndrome. This suggests that other therapeutic options may need to be explored for individuals suffering from this condition.
9.5
Vitamin D treatment enhances alertness
We explored the impact of vitamin D treatment on a case of excessive daytime sleepiness (EDS), specifically in the context of chronic fatigue syndrome. A 28-year-old woman was found to have low levels of vitamin D after experiencing four months of overwhelming fatigue and sleepiness, despite being tested for sleep disorders.
After starting vitamin D supplementation, her condition improved remarkably within just two weeks. Along with a boost in alertness, her associated symptoms like muscle pain and headaches began to fade. By the end of the treatment, her score on the Epworth Sleepiness Scale, which measures daytime sleepiness, dropped significantly, indicating much better daytime function.
This case suggests that vitamin D may play a role in improving symptoms commonly linked to chronic fatigue syndrome. While more research is needed to fully understand the mechanisms behind this improvement, our findings open the door to potentially screening patients with chronic fatigue for vitamin D deficiency to expedite treatment.
After starting vitamin D supplementation, her condition improved remarkably within just two weeks. Along with a boost in alertness, her associated symptoms like muscle pain and headaches began to fade. By the end of the treatment, her score on the Epworth Sleepiness Scale, which measures daytime sleepiness, dropped significantly, indicating much better daytime function.
This case suggests that vitamin D may play a role in improving symptoms commonly linked to chronic fatigue syndrome. While more research is needed to fully understand the mechanisms behind this improvement, our findings open the door to potentially screening patients with chronic fatigue for vitamin D deficiency to expedite treatment.
References
- Noce A, Marrone G, Di Lauro M, Vita C, Montalto G, et al. Potential Anti-Inflammatory and Anti-Fatigue Effects of an Oral Food Supplement in Long COVID Patients. Pharmaceuticals (Basel). 2024;17. 10.3390/ph17040463
- Witham MD, Adams F, McSwiggan S, Kennedy G, Kabir G, et al. Effect of intermittent vitamin D3 on vascular function and symptoms in chronic fatigue syndrome--a randomised controlled trial. Nutr Metab Cardiovasc Dis. 2015;25:287. 10.1016/j.numecd.2014.10.007
- McCarty DE. Resolution of hypersomnia following identification and treatment of vitamin d deficiency. J Clin Sleep Med. 2010;6:605.
